Development of a methodology for in vivo follow-up of hepatocellular carcinoma in hepatocyte specific Trim24-null mice treated with myo-inositol trispyrophosphate.
Mihaela IgnatCherif Youssef AkladiosVéronique LindnerKonstantin KhetchoumianMarius TeletinDidier MuttterPierre Marc AprahamianJacques MarescauxPublished in: Journal of experimental & clinical cancer research : CR (2016)
ITPP treatment allowed for a two-month survival improvement, with better tolerance of tumor burden and apoptosis increase in non-tumor, pathological livers.