In Vitro Chondrogenic Differentiation of Human Adipose-Derived Stem Cells by Diacerein.

Ali Honarpardaz Morteza Daliri JoupariSajjad Tavakkoli

Published in: Iranian journal of pharmaceutical research : IJPR (2023)

We observed that diacerein alone could initiate and enhance chondrogenesis, and it can be used as a differentiation factor for stem cells to chondrocyte besides its ability to inhibit IL-1β. Knowing the actual function of diacerein, it could be a good candidate for the treatment of osteoarthritis.

Keyphrases

stem cells
endothelial cells
mesenchymal stem cells
rheumatoid arthritis
induced pluripotent stem cells
cell therapy
knee osteoarthritis
smoking cessation