A prospective evaluation of the diagnostic accuracy of the point-of-care VISITECT CD4 Advanced Disease test in seven countries.

Tinne GilsJerry HellaBart K M JacobsBianca SossenMadalo MukokaMonde MuyoyetaElizabeth NakabugoHung Van NguyenSasiwimol UbolyamAurélien MacéMarcia VermeulenSarah NyanguNsala SanjaseMohamed SasamaloHuong Thi DinhThe Anh NgoWeerawat ManosuthiSupunnee JirajariyavejClaudia M DenkingerNhung Viet NguyenAnchalee AvihingsanonLydia NakiyingiRita SzékelyAndrew D KerkhoffPeter MacPhersonGraeme MeintjesKlaus ReitherMorten Ruhwald

Published in: The Journal of infectious diseases (2024)

VISITECT's sensitivity, but not specificity, met the World Health Organization's minimal sensitivity and specificity threshold of 80% for point-of-care CD4 tests. VISITECT's quality needs to be assessed and its accuracy optimized. VISITECT´s utility as CD4 triage test should be investigated.

Keyphrases

emergency department
nk cells
tyrosine kinase
high resolution
mass spectrometry
atomic force microscopy