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More than Mycobacterium tuberculosis: site-of-disease microbial communities, and their functional and clinical profiles in tuberculous lymphadenitis.

Georgina R NyawoCharissa C NaidooBenjamin WuImran SulaimanJose C ClementeYonghua LiStephanie MinniesByron W P ReeveSuventha MoodleyCornelia RautenbachColleen WrightShivani SinghAndrew WhitelawPawel SchubertRobin WarrenLeopoldo SegalGrant Theron
Published in: Thorax (2022)
-dominated dTBL lymphotypes, which contain taxa potentially targeted by TB treatment, were associated with milder, potentially earlier stage disease. These investigations lay foundations for studying the microbiome's role in lymphatic TB. The long-term clinical significance of these lymphotypes requires prospective validation.
Keyphrases
  • mycobacterium tuberculosis
  • lymph node
  • cancer therapy
  • drug delivery
  • replacement therapy