CHIPIN: ChIP-seq inter-sample normalization based on signal invariance across transcriptionally constant genes.

Lélia PolitGwenneg KerdivelSebastian GregoricchioMichela EspositoChristel GuilloufValentina Boeva

Published in: BMC bioinformatics (2021)

The CHIPIN method provides a new way for ChIP-seq signal normalization across conditions when spike-in experiments are not available. The method is implemented in a user-friendly R package available on GitHub: https://github.com/BoevaLab/CHIPIN.

Keyphrases

genome wide
single cell
rna seq
high throughput
circulating tumor cells
dna methylation
transcription factor
bioinformatics analysis
low cost
genome wide identification