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Synthesis of 3-Allylindoles via Annulation of N -Allyl-2-ethynylaniline Derivatives Using a P,Olefin Type Ligand/Pd(0) Catalyst.

Takashi MinoToshiki YamaokaKohei WatanabeChihiro MasudaShohei KasanoYasushi YoshidaRyo TakitaYoshio KasashimaMasami Sakamoto
Published in: The Journal of organic chemistry (2022)
Annulation of N -allyl-2-ethynylaniline derivatives easily afforded the corresponding 2-substituted 3-allylindole derivatives in good to excellent yields using P,olefin ligand/palladium catalst systems.
Keyphrases
  • structure activity relationship
  • reduced graphene oxide
  • ionic liquid
  • molecular docking
  • room temperature
  • highly efficient
  • carbon dioxide