Development and preclinical evaluation of virus-like particle vaccine against COVID-19 infection.

Ismail Cem YilmazEmre Mert Ipekoglu Artun Bulbul Nilsu TurayMuzaffer YildirimIrem EvciliNaz Surucu YilmazNese GuvencliYagmur AydinBilgi GungorBerfu SaraydarAsli Gulce BartanBilgehan IbibikTugce Bildikİlayda BaydemirHatice Asena SanliBasak KayaogluYasemin CeylanTugce YildirimIrem AbrasIhsan Cihan AyanogluSefa Burak CamEda Çiftci Dede Merve GizerOsman ErganisFahriye SaracSerdar UzarHakan EnulCumhur AdiayGamze AykutHivda PolatIsmail Selim YildirimŞaban TekİnGulay KorukluogluHasan Ersin ZeytinPetek Korkusuz İhsan GÜrsel Mayda Gursel

Published in: Allergy (2021)

These data suggest that VLPs expressing all four structural protein antigens of SARS-CoV-2 are immunogenic and can protect animals from developing COVID-19 infection following vaccination.

Keyphrases

sars cov
respiratory syndrome coronavirus
electronic health record
big data
dendritic cells
protein protein
cell therapy
amino acid
binding protein
stem cells
data analysis
small molecule
deep learning