Blood eosinophils associate with reduced lung function growth in adolescent asthmatics.

Hans Jacob Lohne Koefoed Ulrike GehringJudith M VonkGerard H Koppelman

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2021)

Blood eosinophil counts in children with asthma not treated with ICS at referral were predictive of lower growth in FEV1 and FVC during follow-up in adolescence. Our findings indicate that this association is dependent on the degree of asthma severity. Future studies should address whether anti-eosinophilic treatments preserve lung function growth in children with asthma.

Keyphrases

lung function
chronic obstructive pulmonary disease
cystic fibrosis
air pollution
young adults
primary care
depressive symptoms
current status