IgE and IgG4 binding to lentil epitopes in children with red and green lentil allergy.
Cansin SackesenBaran ErmanGustavo GimenezGalina GrishinaOzlem YilmazSuleyman Tolga YavuzÜmit Murat ŞahinerBetul BuyuktiryakiEbru A YilmazOzlem CavkaytarHugh A SampsonPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2019)
IgG4-binding epitopes in lentil allergy were identified and IgE and IgG4 binding to epitopes in both red and green lentils was compared. Our data regarding signal intensity differences between reactive and outgrown patients and overlap binding of IgE and IgG4 antibodies may be important for the development of more accurate diagnostic tests and understanding of natural tolerance development.