Effect of Sitagliptin on Kidney Function and Respective Cardiovascular Outcomes in Type 2 Diabetes: Outcomes From TECOS.

Jan H CornelGeorge L BakrisSusanna R StevensMichael AlvarssonWillem A BaxLee-Ming ChuangSamuel S EngelRenato D LopesDarren K McGuireAxel RiefflinHelena Wachslicht RodbardIsaac SinayTsvetalina TankovaJulio WainsteinEric D PetersonRury R Holmannull null

Published in: Diabetes care (2016)

Impaired kidney function is associated with worse cardiovascular outcomes. Sitagliptin has no clinically significant impact on cardiovascular or CKD outcomes, irrespective of baseline eGFR.

Keyphrases

type diabetes
small cell lung cancer
glycemic control
chronic kidney disease
epidermal growth factor receptor
cardiovascular disease
insulin resistance
adipose tissue
skeletal muscle