Diabetes insipidus and Guillain-Barré-like syndrome following CAR-T cell therapy: a case report.
Christian KochJuliane FleischerTodor PopovKarl FrontzekBettina SchreinerPatrick RothMarkus G ManzSimone UnseldAntonia M S MüllerNorman F RusskampPublished in: Journal for immunotherapy of cancer (2023)
This case report highlights the risk of rare but severe neurological adverse events, such as acute GBS or cDI, in patients treated with CAR-T cells. It further underlines the importance of appropriate patient surveillance and systematic reporting of rare complications to eventually improve treatment.
Keyphrases
- case report
- cell therapy
- type diabetes
- liver failure
- stem cells
- mesenchymal stem cells
- public health
- cardiovascular disease
- drug induced
- respiratory failure
- early onset
- emergency department
- adverse drug
- glycemic control
- metabolic syndrome
- intensive care unit
- adipose tissue
- hepatitis b virus
- insulin resistance
- mechanical ventilation
- extracorporeal membrane oxygenation