Additional Effects of Nutritional Antioxidant Supplementation on Peripheral Muscle during Pulmonary Rehabilitation in COPD Patients: A Randomized Controlled Trial.
Farés GouziJonathan MauryNelly HéraudNicolas MolinariHéléna BertetBronia AyoubMarine BlaquièreFrançois BughinPhilippe De RigalMagali PoulainJoël PincemailJean-Paul CristolDalila Laoudj-ChenivesseJacques MercierChristian PréfautPascal PomiesMaurice HayotPublished in: Oxidative medicine and cellular longevity (2019)
While the primary outcome was not significantly improved, COPD patients demonstrate significant improvements of secondary outcomes (muscle strength and other training-refractory outcomes), suggesting a potential "add-on" effect of the nutritional antioxidant supplementation (vitamins C and E, zinc, and selenium) during PR. This trial is registered with NCT01942889.
Keyphrases
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- chronic obstructive pulmonary disease
- prognostic factors
- clinical trial
- type diabetes
- study protocol
- pulmonary hypertension
- adipose tissue
- patient reported outcomes
- climate change
- risk assessment
- cystic fibrosis
- weight loss
- glycemic control
- phase ii