Bladder underactivity after prolonged stimulation of somatic afferent axons in the tibial nerve in cats.

Shun LiKatherine TheisenJeffery BrowningBing ShenJicheng WangJames R RoppoloWilliam C de GroatChangfeng Tai

Published in: Neurourology and urodynamics (2018)

The results indicate that prolonged and intense activation of somatic afferent axons in the tibial nerve can suppress the central reflex mechanisms controlling micturition. This animal model may be useful for examining the pathophysiology of neurogenic bladder underactivity and for development of new treatments for underactive bladder symptoms.

Keyphrases

spinal cord injury
total knee arthroplasty
urinary tract
copy number
peripheral nerve
gene expression
depressive symptoms