Sjögren syndrome and RFC1-CANVAS sensory ganglionopathy: co-occurrence or misdiagnosis?
Gorka Fernández-EulateRabab DebsThierry MaisonobePhilippe LatourFleur Cohen-AubartDavid SaadounOlivier BenvenisteKristl G ClaeysPublished in: Journal of neurology (2022)
The suspicion or diagnosis of pSS in a patient with SG should not exclude RFC1 expansion analysis, as a CANVAS diagnosis may dissuade the clinician from initiating or continuing immunosuppressive therapy, especially in unconfirmed pSS patients. Importantly, a sicca syndrome may lead to pSS misdiagnosis.