Atom-transfer radical addition of fluoroalkyl bromides to alkenes via a photoredox/copper catalytic system.

Vladislav S KostromitinArtem A ZemtsovVladimir A KokorekinVitalij V Levin Alexander D Dilman

Published in: Chemical communications (Cambridge, England) (2021)

A method for the addition of fluorinated alkyl bromides to alkenes is described. The reaction proceeds under visible light irradiation in the presence of two catalysts: Ir(ppy)3 and N-heterocyclic carbene ligated copper bromide (IMesCuBr). The role of the iridium photocatalyst is to generate the fluoralkyl radical, while the copper promotes formation of the carbon-bromine bond.

Keyphrases

visible light
oxide nanoparticles
electron transfer
highly efficient
molecular dynamics
radiation therapy
ionic liquid