Partially local three-way alignments and the sequence signatures of mitochondrial genome rearrangements.

Christian Höner Zu SiederdissenMatthias BerntChristian Höner Zu SiederdissenKifah ToutPeter F Stadler

Published in: Algorithms for molecular biology : AMB (2017)

The partially local sequence alignment method is an effective way to investigate the mechanism of genomic rearrangement events. While applied here only to mitogenomes there is no reason why the method could not be used to also consider rearrangements in nuclear genomes.

Keyphrases

genome wide
oxidative stress
copy number
gene expression