Decoding MRI-informed brain age using mutual information.
Jing LiLinda Chiu Wa LamHanna LuPublished in: Insights into imaging (2024)
Mutual information (MI) interprets estimated brain age with morphometric features. Gray matter volume in the pre-central gyrus has the highest MI value for estimated brain age. Cerebrospinal fluid volume in the cingulate has the highest MI value. Regarding brain parenchymal volume, the superior frontal gyrus has the highest MI value. The value of mutual information underscores the key brain regions related to brain age.