The burden and management of cytochrome P450 2D6 (CYP2D6)-mediated drug-drug interaction (DDI): co-medication of metoprolol and paroxetine or fluoxetine in the elderly.

Muh Akbar BaharEelko HakJens H J BosSander D BorgsteedeBob Wilffert

Published in: Pharmacoepidemiology and drug safety (2017)

Despite the signalling software, metoprolol-paroxetine/fluoxetine combinations are still observed in the elderly population. The clinical impact of these interactions needs further investigation. Copyright © 2017 John Wiley & Sons, Ltd.

Keyphrases

adverse drug
middle aged
community dwelling
healthcare
drug induced
risk factors
emergency department