Use of platelet-rich fibrin for the treatment of periodontal intrabony defects: a systematic review and meta-analysis.

Richard J MironVittorio MoraschiniMasako Fujioka-KobayashiYufeng ZhangTomoyuki KawaseRaluca CosgareaSoren JepsenMark BisharaLuigi CanulloYoshinori ShirakataReinhard GruberDöri FerencMonica Diuana Calasans-MaiaHom-Lay WangAnton Sculean

Published in: Clinical oral investigations (2021)

The use of PRF in conjunction with OFD statistically significantly improved PD, CAL, and RBF values, yielding to comparable outcomes to OFD/BG. The combination of PRF with bone grafts or small biomolecules may offer certain clinical advantages, thus warranting further investigations.

Keyphrases

bone mineral density
type diabetes
soft tissue
skeletal muscle
adipose tissue
metabolic syndrome
body composition
replacement therapy
postmenopausal women