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CD8 + tissue-resident memory T cells are expanded in primary Sjögren's disease and can be therapeutically targeted by CD103 blockade.

Daniele MauroXiang LinElena PontariniPascale WehrGiuliana GugginoYuan TangChong DengSaviana GandolfoFan XiaoKe RuiEnyu HuangJie TianStefania RaimondoMaureen RischmuellerJane BorokySarah Downie-DoyleHendrik NelAdriana Baz-MorelliArthur HsuEugene MaraskovskyAdele BarrPatrice HemonLoukas G ChatzisCiro Emiliano BoschettiGiuseppe ColellaRiccardo AlessandroAroldo RizzoJacques-Olivier PersMichele BombardieriRanjeny ThomasLiwei LuFrancesco Ciccia
Published in: Annals of the rheumatic diseases (2024)
Trm cells are expanded in the SG of pSS and ESS, participate in tissue inflammation and can be therapeutically targeted.
Keyphrases
  • induced apoptosis
  • cancer therapy
  • oxidative stress
  • cell cycle arrest
  • nk cells
  • working memory
  • quality improvement
  • endoplasmic reticulum stress
  • rheumatoid arthritis