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Long-term Metabolic and Socioeducational Outcomes of Transient Neonatal Diabetes: A Longitudinal and Cross-sectional Study.

Fleur Le BourgeoisJacques BeltrandBaz BazJean-Baptiste JullaJean-Pierre RivelineAlbane SimonIsabelle FlechtnerMalek Ait DjoudiAnne-Laure Fauret-AmsellemYoann VialRaphael ScharfmannJulie SommetPhilippe BoudouHélène CavéMichel PolakJean-François GautierKanetee Busiahnull null
Published in: Diabetes care (2020)
Relapse of diabetes occurred earlier in TNDM participants compared with relatives and was associated with puberty. Both groups had decreased educational attainment, and those with diabetes had lower insulin secretion capacity; however, there was no difference in insulin resistance in adulthood. These forms of diabetes should be included in maturity-onset diabetes of the young testing panels, and relatives of TNDM patients should be screened for underlying defects, as they may be treated with drugs other than insulin.
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