A novel approach to label bone marrow-derived mesenchymal stem cells with mixed-surface PAMAM dendrimers.

Nikolas MunroBhairavi SrinageshwarFiras ShalabiMaria FlorendoPaulina OteroCassandra ThompsonJordyn KippeClayton MalkowskiSydney ClimieAndrew N StewartRachel KimJoseph ZhouDouglas SwansonGary L DunbarAjit SharmaJulien Rossignol

Published in: Stem cell research & therapy (2019)

Labeling BM-MSCs using fluorescently tagged PAMAM dendrimers can be used as a potentially safe and efficient method for labeling cells, particularly stem cells, in vitro and in vivo following transplantation in rodents.

Keyphrases

stem cells
bone marrow
mesenchymal stem cells
induced apoptosis
cell therapy
cell cycle arrest
umbilical cord
endoplasmic reticulum stress
signaling pathway