FGFR4 c.1162G > A (p.Gly388Arg) Polymorphism Analysis in Turkish Patients with Retinoblastoma.

Ödemiş Akdeniz Demet Seref Bugra Tuncer Arash Adamnejad Ghafour Khariga Jabbarli Yasemin Gider Betül Çelik Gozde Kuru Turkcan Ozge Sukruoglu Erdogan Seda Kılıç Erciyas Mukaddes Avşar Rejin Kebudi Sema Buyukkapu Bay Samuray Tuncer Yazıcı Hülya

Published in: Journal of oncology (2020)

In patients with advanced retinoblastoma who were diagnosed with retinoblastoma prior to 24 months, the FGFR4 p.Gly388Arg allele was found to be significantly higher. As a result, these results indicate that the polymorphism of FGFR4 p.Gly388Arg may play a role in both the development of tumors and the progression of aggressive tumors.

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