Gene Therapy of Thromboangiitis Obliterans with Growth Factor Plasmid (VEGF165) and Autologous Bone Marrow Cells.

Piotr BarćPawel Lubieniecki Maciej AntkiewiczDiana KupczyńskaJan BarćKatarzyna Frączkowska-SiomaTomasz DawiskibaTadeusz DorobiszWojciech SekulaBłażej CzuwaraMałgorzata Małodobra-MazurDagmara BaczyńskaWojciech WitkiewiczJan Paweł SkóraDariusz Janczak

Published in: Biomedicines (2024)

Gene therapy using the VEGF plasmid along with or without bone marrow-derived mononuclear cells administered intramuscularly into an ischemic limb in TAO is a safe and effective therapy.

Keyphrases

gene therapy
growth factor
bone marrow
induced apoptosis
cell cycle arrest
escherichia coli
mesenchymal stem cells
vascular endothelial growth factor
endothelial cells
crispr cas
signaling pathway
cell death
cell proliferation
brain injury
smoking cessation