The significance of histological activity measurements in immune checkpoint inhibitor colitis.
Rish K PaiReetesh K PaiIan BrownWon-Tak ChoiDavid F SchaefferDavid FarnellM Priyanthi KumarasingheDilini GunawardenaBaek Hui KimMark FriedmanMasoumeh GhayouriGregory Y LauwersPublished in: Alimentary pharmacology & therapeutics (2020)
Histological activity as measured by RHI is the only factor independently associated with biological use and adverse colitis outcomes. Prospective studies are needed to validate these findings to determine if histological activity should be incorporated into therapeutic algorithms.