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Combination of plasma amyloid beta(1-42/1-40) and glial fibrillary acidic protein strongly associates with cerebral amyloid pathology.

Inge M W VerberkElisabeth ThijssenJannet KoelewijnKimberley MaurooJeroen VanbrabantArno de WildeMarissa D ZwanSander C J VerfaillieRik OssenkoppeleFrederik BarkhofBart N M van BerckelPhilip ScheltensWiesje M van der FlierErik StoopsHugo M VandersticheleCharlotte E Teunissen
Published in: Alzheimer's research & therapy (2020)
Combination of plasma Abeta(1-42/1-40) and GFAP provides a valuable tool for the identification of amyloid PET status. Furthermore, plasma GFAP and NfL associate with various disease severity measures suggesting potential for disease monitoring.
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