Germline APOBEC3B deletion influences clinicopathological parameters in luminal-A breast cancer: evidences from a southern Brazilian cohort.
Glauco Akelinghton Freire VitielloNathália de Sousa-PereiraMarla Karine AmaranteBruna Karina Banin HirataClodoaldo Zago CamposKaren Brajão de OliveiraRoberta Losi GuembarovskiMaria Angelica Ehara WatanabePublished in: Journal of cancer research and clinical oncology (2020)
These results show that although A3A/B may not modify BC susceptibility in Brazilian population, it may affect clinicopathological features in BC subtypes, promoting tumor cell proliferation while being negatively associated with LNM in Luminal-A BCs.