Diet-induced obesity causes visceral, but not subcutaneous, lymph node hyperplasia via increases in specific immune cell populations.
A M MagnusonD P ReganJ K FoutsA D BoothS W DowMichelle T FosterPublished in: Cell proliferation (2017)
Overall, HFD has a greater influence on visceral cavity than the subcutaneous. In the visceral lymph node, but not subcutaneous, HFD-induced obesity decreased cell populations that suppressed immune function while increasing those that regulate/activate immune response.
Keyphrases
- insulin resistance
- lymph node
- high fat diet
- high fat diet induced
- metabolic syndrome
- adipose tissue
- immune response
- skeletal muscle
- type diabetes
- weight loss
- neoadjuvant chemotherapy
- sentinel lymph node
- cell therapy
- high glucose
- genetic diversity
- squamous cell carcinoma
- radiation therapy
- early stage
- rectal cancer
- bone marrow
- physical activity