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Patterns of gene evolution following duplications and speciations in vertebrates.

Kyle T DavidJamie R OaksKenneth M Halanych
Published in: PeerJ (2020)
Overall, we found ω to be more similar between lineages descended from speciation events (p < 0.001) than lineages descended from duplication events, providing strong support for the Ortholog Conjecture. The asymmetry in ω following duplication events appears to be largely driven by an increase along one of the paralogous lineages, while the other remains similar to the parent. This trend is commonly associated with neofunctionalization, suggesting that gene duplication is a significant mechanism for generating novel gene functions.
Keyphrases
  • copy number
  • genome wide
  • genome wide identification
  • dna methylation
  • genome wide analysis