Neurotoxicity including posterior reversible encephalopathy syndrome after initiation of calcineurin inhibitors in transplanted methylmalonic acidemia patients: Two case reports and review of the literature.
Femke MolemaMonique WilliamsJanneke G LangendonkSarwa Darwish-MuradJacqueline van de WeteringEd JacobsWillem OnkenhoutEsther BrusseAnke van der EerdenMargreet A E M WagenmakersPublished in: JIMD reports (2020)
In all post-transplanted MMA patients with new neurological symptoms CNI-induced neurotoxicity/PRES should be considered, and directly reducing the dose/discontinuation of CNI is essential.