Activation of kynurenine pathway of tryptophan metabolism after infant cardiac surgery with cardiopulmonary bypass: a prospective cohort study.
Divya SabapathyJelena KlawitterLori SilveiraLudmila KhailovaMax B MitchellGareth J MorganMichael V DiMariaMark TwiteBenjamin S FrankJesse A DavidsonPublished in: Metabolomics : Official journal of the Metabolomic Society (2020)
Infant CPB leads to accumulation of circulating KP metabolites, which have important neurologic and immunologic activities. Thus, further exploration of the KP is warranted in these high-risk infants.
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