Bone mineral density, kidney function, weight gain and insulin resistance in women who switch from TDF/FTC/NNRTI to ABC/3TC/DTG.

F IbrahimA SamarawickramaL HamzahR VincentY GilleeceLaura Jane WatersS KeggB BarbiniL CampbellFrank A Postnull null

Published in: HIV medicine (2020)

Switching from TDF/FTC/NNRTI to ABC/3TC/DTG resulted in improved BMD. Although weight gain was common in women who switched from TDF/FTC/NNRTI to ABC/3TC/DTG, we did not detect adverse effects on glucose homeostasis. Larger studies need to confirm these findings.

Keyphrases

weight gain
bone mineral density
body mass index
birth weight
polycystic ovary syndrome
postmenopausal women
body composition
pregnancy outcomes
weight loss
cervical cancer screening
breast cancer risk
emergency department
pregnant women
blood glucose
insulin resistance
metabolic syndrome
blood pressure