Neoadjuvant Tyrosine Kinase Inhibition in Locally-advanced Non-small Cell Lung Cancer: Two Cases and a Brief Literature Review.
Anish B ParikhLindsay HammonsJorge E GomezPublished in: Anticancer research (2019)
These cases demonstrated that ALK or EGFR mutation-positive stage III NSCLC patients can be treated with the corresponding inhibitors. They also highlight the urgent need for prospective data to assess their potential efficacy in order to improve patient outcomes.
Keyphrases
- tyrosine kinase
- locally advanced
- epidermal growth factor receptor
- small cell lung cancer
- rectal cancer
- advanced non small cell lung cancer
- end stage renal disease
- newly diagnosed
- squamous cell carcinoma
- ejection fraction
- chronic kidney disease
- neoadjuvant chemotherapy
- prognostic factors
- electronic health record
- peritoneal dialysis
- phase ii study
- clinical trial
- big data
- patient reported outcomes
- artificial intelligence