Direct analysis of hydroxylated polycyclic aromatic hydrocarbons in biological samples with complex matrices using polarity-reversed nanoelectrospray ionization.
Siyuan TanJuduo WangManli LiXinchi YinXiaomei GaoChang LiYou JiangXinhua DaiXiaoyun GongXiang FangPublished in: Rapid communications in mass spectrometry : RCM (2022)
The optimized PR-nESI method was successfully applied for the sensitive analysis of OH-PAHs in complex biological samples with severe salt effects. Based on the present study, PR-nESI can have a promising prospect for the sensitive analysis of other metabolites of environmental pollutants in negative polarity.