Direct analysis of hydroxylated polycyclic aromatic hydrocarbons in biological samples with complex matrices using polarity-reversed nanoelectrospray ionization.

Siyuan TanJuduo WangManli LiXinchi YinXiaomei GaoChang LiYou JiangXinhua DaiXiaoyun GongXiang Fang

Published in: Rapid communications in mass spectrometry : RCM (2022)

The optimized PR-nESI method was successfully applied for the sensitive analysis of OH-PAHs in complex biological samples with severe salt effects. Based on the present study, PR-nESI can have a promising prospect for the sensitive analysis of other metabolites of environmental pollutants in negative polarity.

Keyphrases

polycyclic aromatic hydrocarbons
heavy metals
ms ms
human health
early onset
current status
risk assessment
high resolution
simultaneous determination