Respiratory deficits in a female rat model of Parkinson's disease.
Tomás de la RosaViviam Sanabria CalvoValeria C GonçalvesCaroline B FerreiraLais M CabralFelipe da Costa SouzaDébora A ScerniFúlvio A ScorzaThiago S MoreiraAna C TakakuraPublished in: Experimental physiology (2022)
) changes independently of 6-OHDA administration. Notably, there is a reduction in the number of retrotrapezoid nucleus Phox2b neurons and hypercapnia-induced respiratory changes in PD-OVX animals due to a 6-OHDA and OVX interaction. These results suggest a protective effect induced by ovarian hormones in neuroanatomical changes observed in a female experimental PD model.