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Mindray BC-6800 haematological analyser: 3D-DIFF scattergram usefulness in infectious mononucleosis diagnosis.

Antonio La GioiaMaurizio FumiFabiana FioriniMaria BombaraNicola La GioiaYlenia PancioneSilvia SaleMarcello FioriniVincenzo Rocco
Published in: International journal of laboratory hematology (2021)
The additional lymphocyte cluster was significantly associated with activated and apoptotic lymphocytes in samples with serology suggesting ongoing infectious mononucleosis. Considering the significance of clue for infectious mononucleosis assigned to the apoptotic lymphocytes, a specific flag such as "apoptotic cells?" could be associate with the related cluster. Such a flag could be used for dedicated rules for smears review, thus increasing infectious mononucleosis detection in laboratories that do not usually practise instrumental cytograms observation.
Keyphrases
  • cell death
  • peripheral blood
  • cell cycle arrest
  • anti inflammatory
  • induced apoptosis
  • cell proliferation
  • quantum dots
  • real time pcr