Salivary Fluoride Bioavailability after Brushing with Brazilian Red Propolis Dentifrice: A Clinical Study.
Francisco Josimar Girão JúniorLidia Audrey Rocha ValadasPeter BottenbergMara Assef Leitao LotifEdilson Martins Rodrigues NetoSaid Gonçalves da Cruz FonsecaMary Anne Medeiros BandeiraAldo Fabian SquassiThereza Cristina Farias Botelho DantasNara Juliana Custodio de SenaMarta Maria de França FontelesPublished in: Evidence-based complementary and alternative medicine : eCAM (2022)
The results of this study suggest that the propolis incorporated in the dentifrice did not interfere with the kinetics and bioavailability of the fluoride ion in saliva samples, enabling its integration with the pharmaceutical formula and thereby promoting its anti-inflammatory and antimicrobial benefits without compromising the anticaries activity of the formulation.