Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients.
Joanna Dolar-SzczasnyMario Domenico ToroAnna DworzańskaTomasz WójtowiczIzabela Korona-GłowniakRafał SawickiAnastazja BoguszewskaMałgorzata Polz-DacewiczKrzysztof TomasiewiczWojciech ZałuskaRobert RejdakPaola BagnoliDario RuscianoPublished in: International journal of environmental research and public health (2021)
The coronavirus SARS-CoV-2 responsible for the current human COVID-19 pandemic has shown tropism toward different organs with variable efficiency, eyes included. The purpose of this study has been to investigate the presence of detectable SARS-CoV-2 infection in ocular swabs in patients affected by COVID-19. A consecutive series of 74 COVID-19-positive patients (age 21-89) were enrolled at two Polish COVID-19 hospitals for 4 months and were characterized by PCR for the presence of the SARS-CoV-2 genetic material in nasopharyngeal (NP) and ocular swabs, while their respiratory and ocular symptoms were noted. Almost 50% of them presented with severe/critical respiratory involvement, and some degree of eye disease. No tight correlation was observed between the presence of ocular and respiratory symptoms. Three male patients presenting with severe/critical lung disease tested positive in ocular swab, however with mild/moderate ocular symptoms. In conclusion, our study lends further support to the view that overt ocular infection by the SARS-CoV-2 virus is not such a frequent occurrence.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- end stage renal disease
- coronavirus disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- healthcare
- endothelial cells
- risk assessment
- depressive symptoms
- blood brain barrier
- gene expression
- dna methylation
- patient reported outcomes
- optical coherence tomography
- high intensity
- copy number