Boron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses.

Chu-Yu HuangZih-Yin Lai Tzu-Jung HsuFong-In ChouHong-Ming LiuYung-Jen Chuang

Published in: Journal of hepatocellular carcinoma (2022)

Our data suggest that DNA damage and repair responses could affect the anticancer efficiency of BNCT in radioresistant HepG2-R cells, which highlights the potential of BNCT as a viable treatment option for recurrent HCC.

Keyphrases

dna damage
oxidative stress
induced apoptosis
dna repair
cell cycle arrest
big data
endoplasmic reticulum stress
signaling pathway
risk assessment
human health
combination therapy
cell proliferation
machine learning
mesenchymal stem cells
pi k akt