Analysis of key genes and signaling pathways involved in Helicobacter pylori-associated gastric cancer based on The Cancer Genome Atlas database and RNA sequencing data.
Yi HuCong HeJian-Ping LiuNian-Shuang LiChao PengYao-Bin Yang-OuXiao-Yu YangNong Hua LuYin ZhuPublished in: Helicobacter (2018)
These results indicate that some genes (TP53, CCDC151, CHRNB2, GMPR2, HDGFRP2, VSTM2L) and previously unidentified signaling pathways (eg, the Hippo signaling pathway) might play an important role in H. pylori-associated GC.
Keyphrases
- signaling pathway
- helicobacter pylori
- genome wide
- pi k akt
- single cell
- helicobacter pylori infection
- induced apoptosis
- epithelial mesenchymal transition
- papillary thyroid
- bioinformatics analysis
- genome wide identification
- dna methylation
- electronic health record
- genome wide analysis
- squamous cell
- emergency department
- gene expression
- squamous cell carcinoma
- oxidative stress
- data analysis
- gas chromatography
- deep learning