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Minocycline in Severe Cerebral Amyloid Angiopathy: A Single-Center Cohort Study.

Francesco BaxAndrew Davock WarrenAvia Abramovitz FouksHilde van den BrinkSusanne J van VeluwMariel G KozbergSteven M Greenberg
Published in: Journal of the American Heart Association (2024)
Minocycline appeared safe and generally tolerated in a small group of patients with clinically aggressive cerebral amyloid angiopathy and was associated with reduced ICH recurrence. Determining whether this reduction represents a biological response to minocycline rather than a regression to the mean, however, will require a future controlled treatment trial.
Keyphrases
  • subarachnoid hemorrhage
  • cerebral ischemia
  • current status
  • phase iii
  • early onset
  • phase ii
  • free survival
  • combination therapy