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Myelin endocytosis by brain endothelial cells causes endothelial iron overload and oligodendroglial iron hunger in hypoperfusion-induced white matter injury.

Yuxin LiuXinmei KangJiahao LinYixin LiuSanxin LiuChunyi LiXiaohui DengHuipeng HuangTiemei LiShisi WangDanli LuYuxuan JiangZhengqi LuWei CaiTingting Lu
Published in: CNS neuroscience & therapeutics (2024)
The iron imbalance between BVECs and oligodendroglial lineage cells is a potential therapeutic target in hypoperfusion-induced white matter injury.
Keyphrases
  • white matter
  • high glucose
  • endothelial cells
  • multiple sclerosis
  • diabetic rats
  • cognitive impairment
  • iron deficiency
  • drug induced
  • risk assessment
  • cell proliferation
  • brain injury
  • cerebral ischemia