DOSY Analysis of Micromolar Analytes: Resolving Dilute Mixtures by SABRE Hyperpolarization.

Indrek ReileRuud L E G AspersJean-Max TyburnJames G KempfMartin C FeitersFloris P J T RutjesMarco Tessari

Published in: Angewandte Chemie (International ed. in English) (2017)

DOSY is an NMR spectroscopy technique that resolves resonances according to the analytes' diffusion coefficients. It has found use in correlating NMR signals and estimating the number of components in mixtures. Applications of DOSY in dilute mixtures are, however, held back by excessively long measurement times. We demonstrate herein, how the enhanced NMR sensitivity provided by SABRE hyperpolarization allows DOSY analysis of low-micromolar mixtures, thus reducing the concentration requirements by at least 100-fold.

Keyphrases

ionic liquid
magnetic resonance
high resolution
solid state
mass spectrometry