Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation.

Archit TrivediAanchal MehrotraCaitlin E BaumBrandon LewisTupa BasuroyThomas BlomquistRobert TrumblyFabian Volker FilippVijayasaradhi SetaluriIvana L de la Serna

Published in: Epigenetics & chromatin (2020)

These findings indicate a requirement for BET proteins in the regulation of pigmentation and melanocyte differentiation. We identified changes in pigmentation specific gene expression that occur upon BET inhibition in melanoblasts, melanocytes, and melanoma cells.

Keyphrases

gene expression
dna methylation