A prospective clinical and transcriptomic feasibility study of oral-only hormonal therapy with radiation for unfavorable prostate cancer in men 70 years of age and older or with comorbidity.

Benjamin E OnderdonkPaige L DornCarlos MartinezFauzia ArifDenise CloutierTatjana AnticDaniel W GoldenTheodore KarrisonSean P PitrodaRussell Z SzmulewitzStanley L Liauw

Published in: Cancer (2021)

For men with PCa undergoing RT, oral versus standard ADT may improve 6-month QOL and appears to have a similar impact on androgen-responsive gene expression.

Keyphrases

prostate cancer
gene expression
middle aged
radical prostatectomy
dna methylation
single cell
physical activity
type diabetes
cancer therapy
rna seq
polycystic ovary syndrome
community dwelling
radiation induced
metabolic syndrome
adipose tissue
radiation therapy
skeletal muscle