Real-space navigation testing differentiates between amyloid-positive and -negative aMCI.
Florian SchöberlCauchy PradhanStephanie IrvingKatharina BuergerGuoming XiongGünter KuglerStefan KohlbecherJulia EngmannPhilipp WernerMatthias BrendelErich SchneiderRobert PerneczkyKlaus JahnChristian Peter la FougèrePeter BartensteinThomas BrandtMarianne DieterichAndreas ZwergalPublished in: Neurology (2020)
A+ patients with aMCI perform worse than A- patients with aMCI in egocentric and allocentric route planning because of a more widespread impairment of their cerebral navigation network. Navigation testing in real space is a promising approach to identify patients with aMCI with underlying Alzheimer pathology.