Corneal confocal microscopy to detect early immune-mediated small nerve fibre loss in AL amyloidosis.
Andreas ThimmAlexander CarpinteiroSara OubariMaria PapathanasiouLukas KesslerChristoph RischplerRayaz Ahmed MalikHans Christian ReinhardtTienush RassafKen HerrmannChristoph KleinschnitzMark StettnerTim HagenackerPublished in: Annals of clinical and translational neurology (2022)
Our study is the first to show that CCM allows rapid non-invasive identification of early small nerve fibre damage associated with immune cell infiltration in patients with AL amyloidosis. CCM detects peripheral nerve involvement more sensitively than NCS.