Short Communication: Population Representation in HIV Cure Research: A Review of Diversity Within HIV Cure Studies Based in the United States.
Carly RobertsEmma CreamerCheriko A BooneA Toni YoungManya MagnusPublished in: AIDS research and human retroviruses (2022)
HIV is experienced across diverse populations, with gender and racial/ethnic minority populations bearing a significant proportion of disease. With National Institutes of Health (NIH) placing a priority on the enrollment of women and racial/ethnic minorities into studies, it is important to understand the diversity of participants in research. We sought to characterize how HIV cure research studies report data on diversity. A sampling frame of publications with funding provided by the Martin Delaney Collaboratories for HIV Research in 2019 was reviewed for reporting of demographic data. Of 55 publications that included research on humans/human specimens, only 51% provided any demographic description. There often is insufficient consideration of diversity of populations in HIV cure research. Ameliorating gaps in this regard will require recruitment of diverse populations/specimens and specifications to report demographic data in articles. This will ensure inclusion of diverse participants in HIV cure research from earliest laboratory to eventual phase III studies.
Keyphrases
- antiretroviral therapy
- hiv positive
- hiv testing
- hiv infected
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- men who have sex with men
- healthcare
- clinical trial
- electronic health record
- south africa
- phase iii
- emergency department
- type diabetes
- risk assessment
- mental health
- public health
- health insurance
- machine learning
- polycystic ovary syndrome
- insulin resistance
- adipose tissue
- artificial intelligence
- quality improvement
- health information
- pregnant women
- skeletal muscle
- adverse drug
- deep learning
- phase ii
- fine needle aspiration