Early life seizures and epileptic spasms in STXBP1-related disorders.

Kim M Thalwitzer Julie Xian Danielle M DeCampoShridhar ParthasarathyJan Magielski Katie Rose SullivanJames GossCharlene Son Rigby Michael J Boland Benjamin L Prosser Sarah M Ruggiero Steffen Syrbe Ingo Helbig

Published in: Epilepsia (2024)

We provide a comprehensive assessment of early onset seizures in STXBP1-DEE and show that the risk of epileptic spasms is not increased following a prior history of early life seizures, nor by certain ASMs. Our study provides baseline information for targeted treatment and prognostication in early life seizures in STXBP1-DEE.

Keyphrases

early life
early onset
late onset
temporal lobe epilepsy
health information
combination therapy
smoking cessation