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Mapping circulating serum miRNAs to their immune-related target mRNAs.

Bakhtiyor NosirovJoël BillaudAlexis VandenbonDiego DiezEdward WijayaKen J IshiiShunsuke TeraguchiDaron M Standley
Published in: Advances and applications in bioinformatics and chemistry : AABC (2017)
Immune-related mRNAs have more miRNA binding sites in general, not just for serum miRNAs; likewise, serum miRNAs target many more mRNAs than non-serum miRNAs overall, regardless of whether they are immune related or not. Nevertheless, these two independent phenomena result in a significantly larger number of predicted serum miRNA-immune mRNA interactions than would be expected by chance.
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